Advances and Technical Standards in Neurosurgery. Volume 31 by Pickard J.D., Akalan N.

By Pickard J.D., Akalan N.

This sequence, backed through the ecu organization of Neurosurgical Societies, has already develop into a vintage. quite often, one quantity is released in line with yr. The Advances part offers fields of neurosurgery and similar parts during which very important fresh development has been made. The Technical criteria part gains distinct descriptions of normal techniques to help younger neurosurgeons of their post-graduate education. The contributions are written by way of skilled clinicians and are reviewed via all individuals of the Editorial Board.

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The medial palpebral arteries, two in number (the superior and the inferior), arise from the ophthalmic artery below the trochlea. The supratrochlear artery, a terminal branch of the ophthalmic artery, leaves the orbit in the superomedial part together with the nerve of the same name. The dorsal artery of the nose, another terminal branch of the ophthalmic artery, emerges from the orbit between the trochlea and the medial palpebral ligament. Veins of the Orbit There is a very dense venous network in the orbit, organized around the two ophthalmic veins that drain into the cavernous sinus.

Theor Med 24: 31–58 126. Rainov NG (2000a) A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum Gene Ther 11(17): 2389–2401 127. Rainov NG et al (2000b) Immune response induced by retrovirus-mediated HSV-tk/GCV pharmacogene therapy in patient with glioblastoma multiforme. Gene Ther 7(21): 1853–1858 128. Rainov NG, Kramm CM (2001) Vector delivery methods and targeting strategies for gene therapy of brain tumors.

Gene transfer vectors have to be able to cross the BBB. The induction of immune response for some vectors must be avoided, and the production of viral vectors in large scale has to be optimized. Nevertheless, there is no doubt that none of these problems mentioned above are problems that can not be resolved. Acknowledgement We thank Prof. D. D. for critical reading of the manuscript. References 1. Abelo¤ MD et al (2000) Clinical oncology, 2nd edn. Churchill, Livinstone 2. Alisky JA, Davidson BL (2000) Gene therapy for amyotrophic lateral sclerosis and other motor neuron diseases.

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